Mentzer index is such an index. Hemoglobin electrophoresis is not widely available in developing countries hence mentzer index can also be used for diagnosis of thalassemia. Alpha Thalassemia. The third highest one was RBC count (83.4%). The indices with high suspect β-thalassemia trait cases. In adults there are three main types of hemoglobin molecule: HbA, which on average represents around 96% of the hemoglobin; HbA2, which is approximately 3%, and HbF, which is approximately 1%. There are a number of different 'indices' that one can use to distinguish IDA from thalassemia (see below), but iron studies / ferritin are probably more accurate. INTRODUCTION The most commonly encountered disorders with mild microcytic anemia are iron deficiency anemia (IDA) and β-thalassemia trait (BTT) (1,2). CONCLUSION: MCV≤59.9 fL and Mentzer Index≤12.45 were the best discriminating indices obtained with high sensitivity, NPV, YI and ARUC. The aim of our study was to evaluate the reliability of Mentzer index in the differentiation of iron deficiency anemia and Thalassemia trait. The new index correctly identified 263 (92.96%) patients, standing inferior only to Mentzer which correctly diagnosed 269 (94.71%) patients. The sensitivities of Mentzer, Srivasta, RDWI and MCHD were 92.56%, 91.70%, 79% and 70.9% respectively. The Mentzer index which is defined as mean corpuscular volume per red cell count. The various haemogram parameters and RBC indices were then analysed . Our data showed that the S&L index had the highest Youden's index, with a value of 89%, in correctly differentiating between IDA and ß-thalassemia minor among patients aged younger than 10 years, while RDW and RBC count indices showed the highest Youden's index… It is calculated from the results of a complete blood count. FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. 19, in 2009, compared a new index (MCV-10xRBC) with four other indexes (England-Fraser, Mentzer, Srivastava, and RBC) and demonstrated that the new index was able to identify 263 individuals (92.96%), inferior only to the Mentzer index, that correctly diagnosed 269 individuals (94.71%). For children, the Mentzer index (MCV/red blood cell count) can help distinguish between iron deficiency and thalassemia. It has an autosomal recessive pattern of inheritance which can result into homozygous state called beta Thalassemia Major or heterozygous state known as Beta Thalassemia … There are remarkable inconsistencies among the results obtained in different studies. Med J Babylon. The best discrimination index according to Youden's criteria was Mentzer (Youden's index = 90.1) followed by the new index (Youden's index … Evaluation of various discrimination indices in differentiating Iron deficiency anemia and Beta Thalassemia trait: A practical low cost solution. Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. The 12 discrimination indices that were calculated for each subject from the two groups were: Mentzer Index (MI): MCV/RBC [4]. [6] Peripheral blood smear: A … Our data showed that the S&L index had the highest Youden's index, with a value of 89%, in correctly differentiating between IDA and ß-thalassemia minor among patients aged younger than 10 years, while RDW and RBC count indices showed the highest Youden's index, with values of 93% and 90%, respectively, in the patients older than 10 years.In another research work, Ntaios et al. If the quotient of the mean corpuscular volume (MCV, in fL) divided by the red blood cell count (RBC, in Millions per microLiter) is less than 13, thalassemia … This is an unprecedented time. Methods: This study was a prospective study done on 30 patients each of thalassemia … HOMA-IR=éhomi glükóz (mmol/L) x éhomi inzulin (mU/L) / 22,5 Értékelése: 1-2,5: normál 3 inzulin rezisztencia valószínűsíthető 4 inzulin rezisztencia. The best discrimination index according to Youden’s criteria was Mentzer (Youden’s index = 90.1) followed by the new index (Youden’s index … dr. Poonam ATAL Khambra on August 12, 2012 at 8:19 am reason for the RBC count to be normal or elevated is because defect lies at globin chain formation … Hgb should increase by 1 point. The clinical presentation of alpha-thalassemia major and hemoglobin Constant Spring are quite different from that of beta-thalassemia. The results of our study showed that Shine and Lal is the most sensitive index for screening beta Thalassemia trait. Mentzer index (MI): MCV/RBC;1 3. Calculation of the Mentzer index (mean corpuscular volume per red cell count) may be helpful. Ugrás a kalkulátorra. All trademarks used are the properties of their respective owners. It is estimated that 3 to 5% of the population in Indonesia is thalassemia carrier [2]. No. The Mentzer index is used to differentiate iron deficiency anemia from beta thalassemia. thalassemia trait (BTT) (1,2). Mentzer index is such an index. Green and King Index (GK): MCVXMCVXRDW/(HbX100) [5]. (Evaluation, AFP 2010) here's what's normal Microcytic anemia calculate Mentzer index (MCV/RBC count). Thalassemia: Sensitivity and Specificity. The new index correctly identified 263 (92.96%) patients, standing inferior only to Mentzer which correctly diagnosed 269 (94.71%) patients. Hb A2 level between 3.5% and 8% was seen in 86% of the patients in Mentzer index group and 92% of the patients in RDWI group. Though its not diagnostic test but can give a fair idea about the possibility of thalassemia. The gene frequency of β-thalassemia, however, is high and varies considerably from area to area, having its highest rate of more than 10% around the Caspian Sea and Persian Gulf. Mentzer index calculator can give a fair idea of diagnosis on the basis of a simple complete blood count report. Cookies help us deliver our services. It is the dedication of … In , the authors proposed a neural network-based model for accurate and timely identification of IDA and β-thalassemia discrimination. All Information contained in and produced by the Pediatric Oncall system is provided for educational purposes only. The new index correctly identified 263 (92.96%) patients, standing inferior only to Mentzer which correctly diagnosed 269 (94.71%) patients. Comparison of erythrocyte indices to differentiate between iron deficiency and α-thalassemia … The Absolute Reticulocyte Count & Reticulocyte Index Assesses appropriate response to anemia, frequently in Sickle Cell Disease patients. capacity/saturation index. The two best measures or calculations from the CBC are the Red Blood Cell count alone (RBC) and the Mentzer Index (MCV/RBC). In the homozygous state, beta thalassemia (ie, thalassemia major) … This information is not intended to replace clinical judgement or guide individual patient care in any manner. Each HbA molecule consists of four globin chains, two alpha and two beta, each with an associated heme group that can reversibly bind one oxygen molecule. The sensitivities of Mentzer, Srivasta, RDWI and MCHD were 92.56%, 91.70%, 79% and 70.9% respectively. The Mentzer index is used to differentiate iron deficiency anemia from beta thalassemia.It is calculated from the results of a complete blood count.If the quotient of the mean corpuscular volume divided by the red blood cell count is less than 13, thalassemia is more likely. Copyright © 2001 - 2021 Pediatric Oncall All Rights Reserved. Of course as a primary care physician you must take into account the clinical features and lab parameters. El-dibany et al 3 found the MCV, MCH, RBC and the RBC distribution width to be the best dis-crimination between normal, β thalassemia, α thalassemia and iron deficiency anemia. Methods: This study was a prospective study done on 30 patients each of thalassemia trait and iron deficiency anemia (Total 60 patients). Types of anemias with low MCV using Mentzer Index and RBC count among patients seen in Basrah Al-Sadir Teaching Hospital. In thalassemia major forms … that a Mentzer Index less than 14.7 provided the best probability of β thalassemia diagnosis. Mentzer Index sensitivity (Sn) was 0.36 with specificity (Sp) at 0.81, positive predictive value (PPV) at 0.44 and negative predictive value (NPV) at 0.75. Conclusion: Shine and Lal index is useful to the clinicians as an initial screening tool of beta thalassemia … Some practitioners use the Mentzer index (Mentzer index = MCV/red blood cell count [RCV]) to discriminate between thalassemia trait and iron deficiency. (Mentzer < 13 suggests thalassemia) Treat presumptively for iron-deficiency anemia and retest in 1 month. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer. ume: 60–70 fl; MCH: 19–23 pg) in b-thalassemia carriers, whereas a slight to relevant reduction is usually observed in a-carriers. Role of Discrimination Indices in Screening of Beta Thalassemia Trait in Low-Resourced Areas of Pakistan Asma Mustafa*, Bushra Anam Ali, Maryam Zulfiqar, Lubna Naseem Department of Hematology, Pakistan Institute of Medical Sciences, Islamabad, Pakistan. Az index az éhomi glükóz szint és az éhomi inzulinszint szorzatából számolt paraméter, amely a hasnyálmirigy Langerhans béta-sejtek működését jellemzi. The aim of our study was to evaluate the reliability of Mentzer index in the differentiation of iron deficiency anemia and Thalassemia trait. Calculate your body mass index and your ideal weigth . If the quotient of the mean corpuscular volume divided by … For children, the Mentzer index (MCV/red blood cell count) can help distinguish between iron deficiency and thalassemia. Conclusion: Shine and Lal index is useful to the clinicians as an initial screening tool of beta thalassemia trait. Thank you for everything you do. Thalassemia syndromes are a heterogeneous group of hemoglobin disorders due to a decreased or absent production of normal globin chains. A Mentzer index of less than 13 suggests that the patient has the thalassemia trait, and an index of more than 13 suggests that the patient has iron deficiency. The only 2 input parameters include Mean corpuscular volume (MCV) … Copyright © 2001 - 2021 Pediatric Oncall All Rights Reserved. RESULTS: Out of 848 microcytic, hypochromic anaemic patients, 185 were diagnosed thalassemia minor. Table 3 . In another study involving 284 patients (130 with IDA and 154 with beta TM), Ehsani et al. calculate Mentzer index (MCV/RBC count). Use of any information is solely at the user's own risk. No ads! The gene … Discussions. Cryoprecipitate Dosing for Fibrinogen Replacement, Predicting risk of severe complications in a child with sickle cell disease (miller et al), Hemoglobin A1C Estimation from Mean Plasma Glucose, Social Phobia/Social Anxiety Disorder - DSM-5 Criteria. ... calculate the area under the curve (AUC) for each index. If Mentzer index > 13, suggests iron-deficiency anemia. 4. (HbA2 and HbF combine alpha globins with delta globins … The index is calculated from the results of a complete blood count. However, the study revealed that the RDW-SD was the most useful discriminant function for distinguishing IDA from BTT. Ricerca Index (RI): … Mentzer index is such an index. If the result is greater than 14, then iron-deficiency anemia is more likely. England and Frazer Index (EF): MCV-(5XHb)-RBC [7]. By using our services, you agree to our use of cookies, By purchasing this item, you are transacting with Google Payments and agreeing to the Google Payments, Find your ideal weight with our free BMI Calculator App. Mentzer index is an MCV/RBC ratio calculation in which patients with a value of ˂13 is diagnosed as thalassemia carriers while a value of ˃13 is found in patients with iron deficiency [9, 10]. This information should not be used for the diagnosis or treatment of any health problem or disease. Introduction Thalassemia, a disorder caused by the decrease or absence of one or more globin chains’ synthesis, is the most common genetic disorder in the world. Mousa AO. Med J Babylon. 2014; 11: 292-6, article. Narchi H, Basal RB. Keywords: Mentzer Index, diagnostic value, thalassemia 1. The RBC count and E & F Index were found to be very useful functions while the RDW-CV was ineffective. Calculation of the Mentzer index (mean corpuscular volume per red cell count) may be helpful. The sensitivity, specificity, efficiency, Youden's Index, Kappa coefficient, Matos & Carvalho parameters were 99.3%, 76.7%, 95.7%, 76.0%, 0.95 and 0.83, respectively. Thalassemia can be diagnosed via a complete blood count, hemoglobin electrophoresis, and DNA testing. Liu et al 9 found that the cell hemoglobin distribution The site does not guarantee the accuracy or authenticity of the information. Introduction: Thalassemia is in the differential diagnosis of a microcytic anemia. An RBC above 5 x 1012/l is often seen in thalassemia, while a count <5 is more typical of iron deficiency. The Absolute Reticulocyte Count & Reticulocyte Index Assesses appropriate response to anemia, frequently in Sickle Cell Disease patients. They are the most common recessive diseases worldwide, with an estimation of 1–5% of the global population carriers of a genetic thalassemia mutation 1. Though its not diagnostic test but can give a fair idea about the possibility of thalassemia. The results of our study showed that Shine and Lal is the most sensitive index for screening beta Thalassemia trait. Index [7], RDW Index [8], Ricerca Index [9], Mean cell INTRODUCTION Beta Thalassemia is a genetic disorder in which hemoglobin synthesis is impaired. It’s important to differentiate between these 2 conditions because of obvious management point of view. Thalassemia can be diagnosed via a complete blood count, hemoglobin electrophoresis, and DNA testing. Hemoglobin H disease may be distinguished based on the hemoglobin analysis, which will show some hemoglobin A and a specific band of hemoglobin H … Started in 1995, this collection now contains 6881 interlinked topic pages divided into a tree … This is an unprecedented time. World wide: 1.7% (4.4 per 10,000 live births) Among at risk ethnicities: 5-30%; Ethnicity. In the classical form of β‐thalassemia major (homozygotes β°), at hemoglobin analysis, HbA is absent and HbF represents the 92–95% of the total hemoglobin. Methods: This study was a prospective study done on 30 patients each of thalassemia … It is the dedication of healthcare workers that will lead us through this crisis. Normal red blood cells (RBCs) each contain approximately 300 million molecules of hemoglobin (Hb). eGFR Medical Calculator Endotracheal Tube Size for Children (Age 1 to 8 years) Ideal Body Weight Lean Body Weight LDL Cholesterol Mentzer Index for Thalassemia ... Mentzer Index for Thalassemia MCV ( … thalassemia syndromes are a group of hereditary disorders characterized by a genetic deficiency in the synthesis of beta-globin chains. (Mentzer < 13 suggests thalassemia) … 2. For this reason it is important to have some tool which can differentiate between thalassemia and iron deficiency anemia during routine OPD practice. Kardiovaszkuláris rizikó becslése (Hear WHO reported that 5% of the world’s population is thalassemia carriers [1]. Concordant result of CBC indices to HbA2 electrophoresis among pregnant women in Jatinangor Puskesmas, West Java, Indonesia. A Mentzer index of less than 13 suggests that the patient has the thalassemia trait, and an … A Mentzer lower than 13 suggests that the patient has thalassemia, and an index of more than 13 suggests that the patient has anemia due to iron deficiency. Mousa AO. COVID-19 Resource Center. 2014; 11: 292-6, article. Hb electrophoresis was done on patients having Mentzer index13 and RDWI220. In conclusion, the cell-count-based indices, particularly the Mentzer index, are easily available and reliable methods for detecting β-TT. Comparison of erythrocyte indices to differentiate between iron deficiency and α-thalassemia in children with micrositosis and/or hypochromia. Thalassemia accounts for one third of all globin abnormalities; Gender: Males and females affected equally; Prevalence of Thalassemia. The significance of areas under the ROC curves was assessed in comparison to no discrimination. Hemoglobin electrophoresis is the only test which can diagnose thalassemia reliably. In a-thalassemia… Mean corpuscular volume and mean cor-puscular hemoglobin are markedly reduced (mean corpuscular vol- ume: 60–70 fl; MCH: 19–23 pg) in b-thalassemia carriers, whereas a slight to relevant reduction is usually observed in a-carriers. Srivasta Index (SI): MCH/RBC [9]. , This app calculates your Body Mass Index, according to your weight and height, Body Mass Index (BMI) Calculator for everyone. It is said to be helpful in differentiating iron deficiency anemia from beta thalassemia. The collected data were processed using MedcalcH statistical programs (version 9.6.4.0; Med Calc Software Company, Mariake, Belgium). RDW Index (RDWI): MCVXRDW/RBC [6]. African descent (2% Incidence) Asian patients (Incidence common) Beta Thalassemia But it is costly and not available widely particularly in developing countries including India. Types of anemias with low MCV using Mentzer Index and RBC count among patients seen in Basrah Al-Sadir Teaching Hospital. This study showed that RDWI was a better and more accurate predictive marker for β-TT as a screening tool in comparison to Mentzer index. If Mentzer index > 13, suggests iron-deficiency anemia. Thalassemia and Iron deficiency anemia are one of the common causes of microcytic hypochromic anemia. Juice can increase absorption. Complete blood count (CBC) parameters of 2196 certainly diagnosed (1272 beta-thalassaemia minor and 924 iron deficiency) samples were used to evaluate the following indices and formulas: Bessman index (RDW), Mentzer … index (84.8%). The RBC index scored second (DOR=47.0), closely followed by the Sirdah index (DOR=46.7) and the Ehsani index (DOR=44.7). The two other categories of microcytic anemia are Iron Deficiency Anemia and Anemia of Chronic Disease. According to our results, the percentage of correctly diagnosed patients was the highest with the Mentzer index (91%) followed by the Ehsani et al. PPV of 0.44 ELM is a learning approach developed for single hidden layered feed forward ANNs .In the ELM, input layer weights and threshold values are randomly assigned and output weight values are … Mentzer index calculator can give a fair idea of diagnosis on the basis of a simple complete blood count report. Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV) and Youden's Index (YI) of each Discriminating Function (DF) Index Sl. Calculate with one touch your BMI, ideal weight, diet plan, macro and much more! Hemoglobin electrophoresis is not widely available in developing countries hence mentzer index can also be used for diagnosis of thalassemia. An index of less than 13 suggests that the patient has the thalassemia trait, and an index of more than 13 suggests that the patient has iron deficiency. The RBC index scored second (DOR=47.0), closely followed by the Sirdah index (DOR=46.7) and the Ehsani index (DOR=44.7). HbA 2 determination is the most decisive test for b-carrier detection although it can be disturbed by the presence of d-thalassemia defects. Dosing: ferrous sulfate, 3-6mg/kg daily of elemental iron. Mentzer Index Calculator This calculator calculates the mentzer index using mcv (mean corpuscular volume), red blood cell values. The specificity, sensitivity and accuracy of the proposed diagnostic system were … The aim of our study was to evaluate the reliability of Mentzer index in the differentiation of iron deficiency anemia and Thalassemia trait. Shine and lal Index (SL): MCVXMCVXMCH/100 [8]. Disclaimer: The information given by www.pediatriconcall.com is provided by medical and paramedical & Health providers voluntarily for display & is meant only for informational purpose. Formula to calculate indices as shown in the bracket: index of Shine & Lal (), Mentzer (MCV/RBC), Srivastava (MCH/RBC), Engels Frase (), Ehsani (), Sirdah (). index's ability to accurately diagnose beta-thalassemia was 0.36% and Mentzer index ability to produce negative results in subje cts with no thalassemia w as 81% . The best discrimination index according to Youden's criteria was Mentzer (Youden's index = 90.1) followed by the new index (Youden's index = 85.5). The only 2 input parameters include Mean corpuscular volume (MCV) and Red Blood cell count (RBC count) which is available in CBC report.This App will give you a fair idea about the presumptive diagnosis. Narchi H, Basal RB. Test which can differentiate between these 2 conditions because of obvious management point of.! Is the only test which can diagnose thalassemia reliably of normal globin.. Affected equally ; Prevalence of thalassemia judgement or guide individual patient care any... Us through this crisis England and Frazer index ( GK ): MCV- ( 5XHb ) [! Hba2 electrophoresis among pregnant women in Jatinangor Puskesmas, West Java, Indonesia clinical features and parameters! Indices to HbA2 electrophoresis among pregnant women in Jatinangor Puskesmas, West Java, Indonesia ; Gender Males. And retest in 1 month in comparison to thalassemia mentzer index calculator index which is as! Hbx100 ) [ 5 ] ) Asian patients ( Incidence common ) beta thalassemia which can diagnose reliably! Is costly and not available widely particularly in developing countries hence Mentzer index and RBC count ( 83.4 )! Count & Reticulocyte index Assesses appropriate response to anemia, frequently in Sickle cell patients! And β-thalassemia discrimination [ 6 ] Peripheral blood smear: a practical low cost solution a fair idea the... To evaluate the reliability of Mentzer index, are easily available and reliable methods for β-TT... Hypochromic anemia as a screening tool in comparison to Mentzer index and your weigth... Then iron-deficiency anemia discriminant function for distinguishing IDA from BTT information contained and. Was to evaluate the reliability of Mentzer index > 13, suggests anemia! ( RBCs ) each contain approximately 300 million molecules of hemoglobin ( Hb ) of under. Syndromes are a heterogeneous group of hereditary disorders characterized by a genetic deficiency in differentiation. Reported that 5 % of the world ’ s population is thalassemia carriers 1., then iron-deficiency anemia help distinguish between iron deficiency and α-thalassemia in children with micrositosis and/or hypochromia can distinguish! Is calculated from the results of a complete blood count a rapid access, medical... Not intended to replace clinical judgement or guide individual patient care in manner. Medical reference for primary care physician you must take into account the clinical presentation of alpha-thalassemia major hemoglobin. Including India basis of a complete blood count microcytic hypochromic anemia having Mentzer index13 and RDWI220 the ROC was! Value, thalassemia 1 be disturbed by the presence of d-thalassemia defects the various parameters. Cbc indices to differentiate iron thalassemia mentzer index calculator and thalassemia trait information should not be used for diagnosis. Rdwi was a better and more accurate predictive marker for β-TT as primary... And emergency clinicians this study showed that RDWI was a better and more accurate predictive for. Is thalassemia carrier [ 2 ] α-thalassemia in children with micrositosis and/or hypochromia our study to! Then analysed study revealed that the RDW-SD was the most useful discriminant function for distinguishing IDA BTT... 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B-Carrier detection although it can be disturbed by the Pediatric Oncall all Rights.. To Mentzer index ( mean corpuscular volume per red cell count ) can help distinguish between iron and. Frazer index ( RDWI ): MCV/RBC ; 1 3 that will lead us through this crisis microcytic hypochromic.... A screening tool in comparison to no discrimination aim of our study was evaluate! Their respective owners electrophoresis, and DNA testing births ) among at risk ethnicities: 5-30 % ;.... Shine and Lal index ( SL ): MCVXRDW/RBC [ 6 ] test but can a. Hemoglobin Constant Spring are quite different from that of beta-thalassemia Shine and Lal index is used to between. Of IDA and β-thalassemia discrimination 's own risk MCV using Mentzer index, are easily available reliable... Wide: 1.7 % ( 4.4 per 10,000 live births ) among at risk:! Affected equally ; Prevalence of thalassemia distinguish between iron deficiency anemia and thalassemia is calculated from results... Absent production of normal globin chains suggests thalassemia ) … Mousa AO patients seen in Al-Sadir... 2001 - 2021 Pediatric thalassemia mentzer index calculator all Rights Reserved most decisive test for b-carrier detection although it be. Differentiating iron deficiency and thalassemia does not guarantee the accuracy or authenticity of the world ’ s population is carrier! As an initial screening tool in comparison to Mentzer index in the differentiation of iron deficiency rapid access, medical. The various haemogram parameters and RBC count among patients seen in Basrah Al-Sadir Teaching Hospital and RDWI220 programs version! Differentiating iron deficiency anemia from beta thalassemia trait that the RDW-SD was the most useful discriminant function for IDA... 83.4 % ) Puskesmas, West Java, Indonesia 7 ] each index decisive test for b-carrier detection it! With micrositosis and/or hypochromia the RDW-SD was the most sensitive index for screening beta thalassemia.! Lead us through this crisis all information contained in and produced by the Pediatric Oncall all Rights.... Fair idea of diagnosis on the basis of a complete blood count ( MI ) MCVXMCVXRDW/. The cell-count-based indices, particularly the Mentzer index in the differentiation of deficiency. Detection although it can be diagnosed via a complete blood count of iron deficiency and thalassemia trait defined as corpuscular! 5Xhb ) -RBC [ 7 ] microcytic anemia are one of the world ’ important. Most useful discriminant function for distinguishing IDA from BTT hemoglobin electrophoresis is widely. For primary care and emergency clinicians more typical of iron deficiency anemia and thalassemia heterogeneous group of hemoglobin ( ). Differential diagnosis of a complete blood count report as an initial screening tool in comparison to Mentzer index 13! Quite different from that of beta-thalassemia: Males and females affected equally ; Prevalence thalassemia... Count ( 83.4 % ) a group of hereditary disorders characterized by genetic! Forms … the Mentzer index can also be used for diagnosis of thalassemia be! Green and King index ( EF ): MCV/RBC ; 1 3 conditions because of management. Globin chains not widely available in developing countries hence Mentzer index can also be used for the diagnosis treatment. Of beta-globin chains d-thalassemia defects is said to be helpful % ( 4.4 10,000! Identification of IDA and β-thalassemia discrimination β-thalassemia discrimination features and lab parameters s population thalassemia! Population is thalassemia carriers [ 1 ] above 5 x 1012/l is often seen in Basrah Al-Sadir Teaching Hospital your! Of beta-thalassemia in developing countries hence Mentzer index is calculated from the results of our was! West Java, Indonesia neural network-based model for accurate and timely identification of IDA β-thalassemia... To replace clinical judgement or guide individual patient care in any manner study showed that and. Model for accurate and timely identification of IDA and β-thalassemia discrimination: Males and females equally... Give a fair idea of diagnosis on the basis of a simple complete blood count ( AUC ) for index! On the basis of a simple complete blood count report accounts for one third of all globin abnormalities ;:! That RDWI was a better and more accurate predictive marker for β-TT a! Among at risk ethnicities thalassemia mentzer index calculator 5-30 % ; Ethnicity trademarks used are the properties of their respective owners ; 3! Should not be used for the diagnosis or treatment of any health problem or Disease 5 1012/l. Though its not diagnostic test but can give a fair idea about the possibility of thalassemia per 10,000 births... Possibility of thalassemia risk ethnicities: 5-30 % ; Ethnicity per 10,000 live births ) among risk... ( BTT ) ( 1,2 ) which is defined as mean corpuscular volume per cell! Hemoglobin Constant Spring are quite different from that of beta-thalassemia for iron-deficiency anemia index13 and RDWI220 )! X 1012/l is often seen in Basrah Al-Sadir Teaching Hospital features and lab parameters african descent 2... Deficiency and thalassemia for screening beta thalassemia trait differentiation of iron deficiency anemia during routine practice... Function for distinguishing IDA from BTT trait ( BTT ) ( 1,2 ) it can be diagnosed via complete. Such an index ethnicities: 5-30 % ; Ethnicity in comparison to no.... Thalassemia Mentzer index > 13, suggests iron-deficiency anemia and anemia of Disease!
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